From Figure 4, we found that female sex, age < 65 years, HTN, BMI ≥ 24 kg/m2, CHA2DS2-VASc score < 2, HAS-BLED score < 3, and EHRA score = 3 combined with high TIMP-1 level could better predict AF recurrence after RFCA. The gene discussed is TIMP1; the disease is hypertensive disorder.