IL17A and hypertensive disorder: We previously reported that peripherally administered IL-17A acts in the brain to amplify the expression of inflammatory cytokines and chemokines produced by astrocytes and microglia to promote neuroinflammation and sympathetic outflow, and IL-17A-elicited neuroinflammation plays an important role in the development of ANG-II induced hypertension (Cao et al., 2021(Cao et al., 2021).