When the therapeutic efficacy of patients with anti-PD-1 plus chemotherapy was divided into CAP/NCCN pathological tumor regression grade 0 (PCR) and grade 1, 2, 3 (non-PCR), our results seemed to show baseline NLR、LMR、PLR、SII could not better predict the pathological tumor regression grade by ROC curve analysis. Here, PDCD1 is linked to neoplasm.