This study found that 13 lncRNAs (ADD3-AS1, AL356019.2, LEF1-AS1, LINC00346, WDR11-AS1, TMEM72-AS1, AC007744.1, AC073896.2, AL392083.1, AC062021.1, AC093726.1, AC093895.1, and NR2F2-AS1), which were inflammation-related based on functional analysis, were differentially expressed in gliomas and normal brain tissue, and they could independently and accurately predict the prognosis of patients. Here, TMEM72 is linked to central nervous system cancer.