ERBB2 and neoplasm: OV-encoded antibody showed direct antitumor activity and triggers ADCC in vitro.Subcutaneous xenograft mouse tumor model/intratumoral virus injection enhanced antitumor efficacy of antibody-encoding OV compared with parental virus or trastuzumab for Her2-positive xenografts.Higher tumor-to-blood antibody concentrations by antibody-encoding OV compared with conventional antibody application (167).