As an examples for this type of combination, Bahrololoumi et al. constructed a bsAb (antiHN scFv/antiCD16 scFv) and a trispecific antibody(antiHN scFv/IL-15/antiCD16 scFv) to bind to the haemagglutinin neuraminidase (HN), a viral protein that is expressed on the surface of the NDV infected tumor cell, and the CD16 activating receptor on the surface of the NK cells for redirecting NK cells toward the tumor cells (201, 202). The gene discussed is MT-RNR2; the disease is neoplasm.