TTF-1 promoter, glypican-3 protein (GPC3), human secretory leukocyte protease inhibitor (hSLPI), Mucin 1 (MUC1), cyclooxygenase 2 (COX2), epithelial glycoprotein (EPG2), and human telomerase reverse transcriptase (hTERT) are the most common tumor-specific promoters used in transcriptional targeting (7). The gene discussed is PTGS2; the disease is neoplasm.