IBSP and neoplasm: The levels of COL5A2, IBSP, COL4A1, AGRN, SPP1, COL11A1, and HMMR in nearly all tumor tissues were significantly elevated compared with those in paired normal tissues; on the contrary, the levels of RELN, ITGA8, TNXB, LAMA2, SV2B, and COL6A6 in nearly all tumor tissues were significantly decreased compared with those in paired normal tissues.