Based on the intersection of results of univariate and Kaplan–Meier survival analyses, we obtained 8 ECMGs truly associated with PAAD prognosis (i.e. ITGB6, ITGA3, LAMC2, ITGA2, LAMA3, ITGB4, COL11A1, and LAMB3). This evidence concerns the gene ITGB4 and pancreatic adenocarcinoma.