Tezepelumab has already successfully completed phase II and III clinical trials, with results indicating a reduction in rates of asthma exacerbations, improved FEV1, and a reduction of T2 inflammatory biomarkers such as IL-5, IL-13 periostin, and IgE in both T2 high and T2 low individuals with severe asthma, and without an increase in adverse effects over those of placebo (157–162, 166). Here, IL13 is linked to asthma.