Previous studies have described the pathways of HLA-G-induced tolerance and the role that these molecules play in autoimmune diseases (67, 68), such as rheumatoid arthritis (69, 70) and systemic lupus erythematosus (71, 72), but so far, no studies have investigated the impact of HLA-G expression on autoimmune hepatitis. Here, HLA-G is linked to autoimmune disease.