RAC1 and sarcoidosis: Similarly, UIC STAR cohort related genes such as RAC1 and ATP6V0D1 have been previously proposed to induce dysfunctional autophagy-related pathways in sarcoidosis and RAC1 and others such as CD300A, CSF3R, G6PD function as drivers of monocyte differentiation or as modulators of the innate immune response and promoters of inflammatory cytokines.