Many of the mutually significant genes, including BATF2, C1QB, CD1D, FCGR1A, ICAM1, IRF1, IL15RA, NOD2, SERPING1, SMARCD3, TYMP, and WARS have been associated with sarcoidosis in other bulk transcriptomic analyses of whole blood and PBMCs and are known to be involved in regulation of innate and adaptive immune responses and cell differentiation (25, 28, 30–32, 61–63). This evidence concerns the gene ICAM1 and sarcoidosis.