Notwithstanding, target genes of TLE3 and CBX8 significantly outperformed the red and lightgreen random gene lists and accurately predicted imputed and clinical CD4+ T-cell abundance in the UIC STAR cohort (Venkatraman test p-value <0.05) further substantiating the association between altered transcription factor targeting and differential PBMC proportions in sarcoidosis. This evidence concerns the gene TLE3 and sarcoidosis.