However, miR-342-3p facilitates the production of cytokines and chemokines such as TNF-α, IL-1, IL-6, and CXCL15 via SOCS6 suppression and subsequent STAT1 activation and switches the death modality from necrosis to apoptosis in M. tuberculosis-infected macrophages, enhancing the anti-TB immune response. This evidence concerns the gene IL1B and tuberculosis.