In order to more intuitively reflect the distribution level of each immune cell in MYCN positive and MYCN negative NB, we drew the corresponding violin diagram, from which we could see that the distribution of 28 immune cells was different in MYCN positive and MYCN negative group (Figure 9B). Except that Activated CD4 T cell and Type2 T helper cells increased, the infiltration levels of the other 26 cells decreased significantly in MYCN positive NB tissues. Here, CD4 is linked to neuroblastoma.