The green cluster mainly contains immunity, immune system, low-density-lipoprotein (LDL), IL-10, atherosclerosis reduction, TGF-β, regulatory t-cells (Tregs), apolipoprotein-e, tolerance, Th17 cells, induction, adaptive immunity, antibodies, autoimmunity, B-cells, CD4(+) T-cells, cytokines, deficient mice, dendritic cells, E-deficient mice, e-knockout mice, Foxp3+, transforming growth-factor-beta, human atherosclerotic plaques, immune-response, immunization, immunology, in-vivo, INF-γ, IL-17, oxidized LDL, receptor-deficient mice, and T cells. The gene discussed is APOE; the disease is atherosclerosis.