The DERRAGs were significantly enriched in 13 cellular components, including lamellar body, lysosomal lumen, vacuolar lumen, meiotic spindle, TORC2 complex, pronucleus, GATOR2 complex, spindle pole centrosome, TOR complex, Seh1-associated complex, germ cell nucleus, endolysosome and microvillus membrane (Figure 3D), and pathways of lysosome, Ras signaling, and bladder cancer (Figure 3E). Here, SEH1L is linked to urinary bladder cancer.