(5) reported that in pregnant women with a high viral load of HBV, the incidence rates of abnormal ALT (ALT > 40 U/L) and severe hepatitis (ALT > 400 U/L) between 5 and 28 weeks postpartum were 45% and 1% in the TDF intervention group and 30% and 3% in the non-intervention group respectively. The gene discussed is GPT; the disease is hepatitis A virus infection.