Our analyses provided unprecedented evidence that the amplified expression of EGFR/ERBB1 mRNA in MM cells was positively correlated with increased expression levels of mRNAs for several DNA binding proteins/transcription factors, including ETF [34-36], SP-1 [37-41], TCF [42,43], HOXB5 [44,45], RPF-1 [46] and AP-1 [33,47-49]. This evidence concerns the gene SP1 and Miyoshi myopathy.