The main goal of the present study was to identify abundantly expressed tyrosine kinases of MM cells as potential therapeutic targets with an emphasis on the relative gene expression levels of for 21 PTK, including ERBB1/epidermal growth factor receptor (EGFR), ERBB2, ERBB3, JAK1, JAK2, JAK3, TYK2, FGR, FLT3, FYN, HCK, LCK, LYN, MERTK, SRC, BLK, BMX, BTK, PTK2, SYK, TEC. Here, JAK3 is linked to Miyoshi myopathy.