Several studies have reported the interaction between galectin-3 and galectin-3 binding protein initiates pathologic, proinflammatory signalling cascades in diseases such as cancer, and venous thrombosis (DeRoo et al., 2015; Newlaczyl and Yu, 2011; Silverman et al., 2012). The gene discussed is LGALS3; the disease is Venous thrombosis.