Quantitative real time RT-PCR revealed a 11.5-fold increase of renal Col1A1 mRNA abundance in WT (1,054 ± 188%, p < 0.01) and a 11.7-fold increase in AnxA1-deficient mice (1,169 ± 113%, p < 0.01) at d10 after nephritis induction (Figure 7B). The gene discussed is ANXA1; the disease is nephritis.