At d10 after nephritis induction, quantification of Sirius Red signal demonstrated only a numerical increase in the signal density in WT (165 ± 47%, p = n.s.)and a significant 13-fold increase (1,285 ± 321%, p < 0.01) in AnxA1-deficient mice as compared to the respective controls. The gene discussed is ANXA1; the disease is nephritis.