Seven studies have shown increased circulating concentrations of thrombomodulin in women with preeclampsia compared with normotensive controls (Hsu et al., 1993; Minakami et al., 1993; Bontis et al., 1995; Hsu et al., 1995; Shaarawy and Didy, 1996; Rousseau et al., 2009; Dusse et al., 2013). Here, THBD is linked to preeclampsia.