Interestingly, mGluR7 is also associated with ARHL and NIHL in humans (Friedman et al., 2009; Newman et al., 2012; Chang et al., 2018; Yu et al., 2018; Matyas et al., 2019), and mGluR7 knockout mice exhibited hearing deficits (Fisher et al., 2020). Here, GRM7 is linked to noise induced hearing loss.