In MS patients, intrathecal synthesis of Igs was detected against measles, rubella, varicella zoster, mumps and EBV, and in most cases, antibodies against more than one virus are present (Arnadottir et al., 1979; Sindic et al., 1994; Kakalacheva et al., 2011). This evidence concerns the gene CUBN and myeloid sarcoma.