In addition, in the brain, an increased expression of CD36 by the microglia and by Ly6Cint and Ly6Clow monocytes was observed before treatment on D3 (Figure 3A and Supplementary Figure S3E), which may reflect the activity of non-opsonic phagocytosis of these populations at this stage of infection or their implication in GPI signaling and the pro-inflammatory response. This evidence concerns the gene CD36 and infection.