Higher plasma Lp(a) levels increase the incidences of PAD and PAD-related hospitalization.8,9) Thus, the concentrations of Lp(a), low-molecular-weight apo(a) phenotypes, and SNPs in the rs10455872 were associated with the progression of PAD, CHD, and aortic valve stenosis.6,16,18). The gene discussed is LPA; the disease is aortic valve stenosis.