Lipoprotein(a) [Lp(a)] is a complex polymorphic lipoprotein composed of a low-density lipoprotein particle and glycoprotein apo(a) through apoB-100.1) Lp(a) shares high-level homology with plasminogen, and Lp(a) activates monocytes and the migration of macrophage foam cells into the arterial wall.1,2) The plasma Lp(a) level is correlated with calcification of coronary artery and coronary heart events.2,3) Several reports have demonstrated that Lp(a) is an independent risk factor for coronary heart disease (CHD) and cerebrovascular disease (CVD).1–3). This evidence concerns the gene AOPEP and coronary artery disorder.