M1/M2 macrophage polarization is regulated by several genes (i.e., spleen tyrosine kinase, bridging integrator 2, metalloproteinase 12, chemokine receptor 5, macrophage mannose receptor 1, and TNF receptor type 1‐associated death domain) that are differentially expressed in endometriosis.45, 46. Here, SYK is linked to endometriosis.