SOD1 and hypertensive disorder: In addition, significantly decreased levels of catalase (Cat), glutathione peroxidase (GPx) and superoxide dismutase (SOD) were evidenced in cardiac and aortic tissue (Sawant and Bodhankar, 2016) and erythrocytes (Kumar et al., 2012) of rats with L-NAME hypertension (Bunbupha et al., 2015).