The AKT, also called protein kinase B, signalling pathway is involved in the molecular mechanisms underlying many cancers, which plays a vital role in tumor cell proliferation, metastasis and drug resistance, lncRNAs can regulate the relative expressions of key genes in the phosphoinositide 3-kinase (PI3K)/AKT pathway (Peng et al., 2017; Lin et al., 2020). Here, AKT1 is linked to cancer.