Th1 cells are an inflammatory fraction of CD4+ T cells that primarily generate interferon-gamma (IFN-γ), an inflammatory cytokine that protects against intracellular pathogens, and is related to delayed-type hypersensitivity, and autoimmune diseases including ITP (Li et al., 2016), (Collier et al., 2012a). The gene discussed is IFNG; the disease is autoimmune thrombocytopenic purpura.