The current study contains several new and important insights; findings suggest that lncRNAs IFNG-AS1 and GAS5 are novel diagnostic and prognostic biomarkers for childhood ITP that can aid in a precise prediction of the disease’s progress at the time of diagnosis and could be a useful tool for treatment planning, reducing the risk of bleeding while avoiding drug side effects. The gene discussed is GAS5; the disease is autoimmune thrombocytopenic purpura.