We previously identified a subpopulation of MARCO- expressing macrophages highly represented in the TME in human breast cancer, metastatic melanoma, periampullary adenocarcinoma (intestinal type), and small cell lung cancer (Georgoudaki et al., 2016; La Fleur et al., 2018; Lundgren et al., 2017). Here, MARCO is linked to periampullary adenocarcinoma.