We found DDX24 was correlated with DKC1, CEP250, PSMD14, INO80, G3BP2, SIRT7, KDM1A, CCND1, FBL, IDO1 and DDX27, functioning as an oncogene in the development of HCC.19–21 Furthermore, we identified the top 50 co-expressed genes of DDX24 in liver cancer samples from the TCGA database and performed an interaction network analysis via the Reactome Pathway (p < .05, Figure 1d). This evidence concerns the gene DDX27 and hepatocellular carcinoma.