AKT1 and hepatocellular carcinoma: A KEGG pathway enrichment analysis revealed that DDX24 was likely involved in crucial biological signaling relating to promotion of HCC progression, including PI3K-Akt-mTOR, apoptosis, JAK-STAT, Notch and the Necroptosis signaling pathways (Figure 1e).22,23 In summary, a high expression of DDX24 is significantly related to patient overall survival, and DDX24 may be involved in the pathways regulating HCC development.