We noticed that 3‐hydroxyanthranilic acid (3‐HAA) produced by catalytic hydrolysis of kynurenine through kynureninase and kynurenine 3‐monooxygenase, was the second most downregulated hit during ischemia, while KYNA was the most upregulated metabolite (Figure 1C; Figure S1C, Supporting Information). Here, KYNU is linked to ischemia.