IGF1R and nasopharyngeal carcinoma: reported that YTHDC2 could enhance the translation initiation of IGF1R mRNA to promote radiotherapy resistance in NPC cells.[13] Although m6A alters mRNA stability and translation, rapidly accumulating evidence highlights the significance of crosstalk between this epitranscriptomic modification and histone epigenetic regulation in physio‐pathological cellular processes.[14] Whether histone methylation modulators can be regulated by m6A modification and, if so, what they do and how they act in NPC development and progression remain to be elucidated.