Importantly, it was observed that CD155 expression was associated with OS of cancer patients in the studies that were published < 3 years ago (pooled HR = 1.805, 95% CI = 1.493–2.182, P < 0.001) and at least 3 years ago (pooled HR = 1.568, 95% CI = 1.127–2.183, P = 0.008). This evidence concerns the gene PVR and cancer.