As summarized in Table 3, a significant correlation was observed between CD155 expression and gender (pooled OR = 0.657, 95% CI = 0.510–0.846, P = 0.001), tumor stage (pooled OR = 1.697, 95% CI = 1.217–2.366, P = 0.002), LN metastasis (pooled OR = 1.953, 95% CI = 1.253–3.046, P = 0.003), and distant metastasis (pooled OR = 2.253, 95% CI = 1.235–4.110, P = 0.008), which indicated that high expression of CD155 was associated with advanced tumor stage and positive of LN metastasis and distant metastasis. Here, PVR is linked to neoplasm.