In this study, the mean length of DRM was longer in GPB group (2.74 ± 0.76 cm vs. 2.16 + 0.68 cm, p < 0.001), especially for low rectal cancer (1.78 ± 0.67 cm vs. 1.23 ± 0.59 cm, p < 0.001). The gene discussed is GYPB; the disease is rectal cancer.