For example, analysis of NCI-high risk children enrolled on AALL0232 showed that 20 MEF2D-r cases belonged to the group with EFS of 72%, which was comparable to BCR::ABL1 (60%), KMT2A-r (78%) and Ph-like (60%), but lower than other BCP-ALL cases (87%) [6]. The gene discussed is OPN1SW; the disease is acute lymphoblastic leukemia.