Moreover, IHC assay data in xenograft tumor tissues revealed that LINC00589 overexpression could upregulate the protein expressions of DLG5 and PRDM16, while miR-100 and miR-452 abrogated the promotion of LINC00589 on the DLG5 and PRDM16, respectively (Fig. 8L). This evidence concerns the gene PRDM16 and neoplasm.