AKT1 and head and neck squamous cell carcinoma: Regarding upstream cellular signalling, the study finds that 7‐Epitaxol reduces the phosphorylation of AKT, ERK1/2 and p38 in cisplatin‐resistant HNSCC cells, leading to cleavage and activation of PARP and caspases 3, 8 and 9 and subsequent induction of apoptosis (Figure 6).