Tong found a succinylation modification on the glutaminase (GLS) protein occurred at the K311 position and was mediated by succinyl‐CoA, which could promote the conversion of GLS from monomer to active tetramer, thereby improving its catalytic activity and enhancing the catabolism of glutamine in pancreatic ductal adenocarcinoma.8 The gene discussed is GLS; the disease is pancreatic ductal adenocarcinoma.