BRCA1 and pancreatic adenocarcinoma: Approximately 0.7%–5.7% and 0.3%–2.3% of unselected cases of pancreatic adenocarcinoma are linked to pathogenic mutations, respectively, in BRCA1 and BRCA2 genes (Rosen et al., 2021), making them the most common cause of familial pancreatic cancer (Pilarski, 2019).