LDHA is known to catalyze the conversion from lactate to pyruvate during glycolytic metabolism,[38, 39, 40] and several studies have reported that the lactate levels are abnormally elevated and positively correlated with poor prognosis in CRC patients.[41, 42, 43] Therefore, we evaluated the effect of EBV‐miR‐BART18‐3p and LDHA expression on intracellular and extracellular lactate and pyruvate levels in CRC cells. The gene discussed is LDHA; the disease is colorectal carcinoma.