Divided by sex (Male group and female group), age (youth group (18–44 years old), middle-aged group (45–59 years old), and elderly group (≥ 60 years old)) and diabetes duration (diabetes duration ≤ 5 years and diabetes duration > 5 years), there was no difference in osteocalcin levels between the groups (respectively, p > 0.05). The gene discussed is BGLAP; the disease is diabetes mellitus.