BRAF and brain neoplasm: However, Schindler et al. noted no significant differences of patient age at surgery for GG with BRAFV600E mutation7; Zhang et al. reported no significant correlation between the BRAF status in GNT and age at surgery, as well as age of seizure onset and duration of epilepsy17; and Xing et al. also didn’t find brain tumors with epilepsy and BRAFV600E mutation were associated with gender and duration of epilepsy6.