Although there is some discrepancy in the terms and pathways between cell lines and tumor tissues due to the heterogenic characteristic of gastric cancer tissues, the terms and pathways regarding cell junctions, proliferation and motility show consistency, supporting the notion that ESRP1 has a critical function in metastasis and tumorigenesis by suppressing tumor motility and invasiveness in gastric cancer cells. This evidence concerns the gene ESRP1 and gastric cancer.