ARHGAP5 and gastric cancer: ARHGAP5 knockdown in DUSP5P1-overexpressing BGC823 and MGC803 cells significantly blunted the promoting effects of DUSP5P1 on cell migration and invasion (Fig. 5G1), while ARHGAP5 overexpression significantly diminished DUSP5P1 KO-mediated inhibition of migration in MGC803 and BGC823 cells (Fig. 5G2), indicating that the tumor-promoting effect of DUSP5P1 is at least in part dependent on ARHGAP5 in GC.