We found increased levels of pATR (Thr1989), pChk1 (Ser345), p-p53 (Ser15), and p95/NBS1 in SLE compared to HC B cells, but no differences in pATM (Ser1981), pChk2 (Thr68), and pDNA-PKcs (Ser2056) levels via immunofluorescence microscopy or flow cytometry (Fig. 2B). The gene discussed is TP53; the disease is systemic lupus erythematosus.