Thus, the expression levels of γH2AX were also evaluated in peripheral T helper (CD4+), T cytotoxic (CD8+), T regulatory (CD4+CD25+Foxp3+), classical monocytes (HLA-DR+CD14+CD16−), intermediate monocytes (HLA-DR+CD14+CD16+), nonclassical monocytes (HLA-DR+CD14−CD16+), and neutrophils (CD66b+) of individuals with SLE and HC. This evidence concerns the gene CD8A and systemic lupus erythematosus.