CTP-phosphocholine-cytidyl transferase alpha (CCTα), the rate-limiting enzyme in the phosphatidylcholine synthesis pathway, lipid droplet-associated lipases adipocyte triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL), as well as several long-chain acyl-CoA synthetases (ACSLs), are implicated in the activation of infection-specific phospholipid synthesis that provides the bulk of membrane material for the expansion of the replication organelles [34–37]. This evidence concerns the gene LIPE and infection.