CXCL12 and central nervous system cancer: Other studies have demonstrated that additional alterations of NK cells to carry an MR1 antibody with C-X-C motif chemokine receptor 4 increased the chemotaxis to C-X-C motif chemokine 12, also known as stromal cell-derived factor 1 generated by glioma cells, leading to higher stability in the circulation compared to NK cells expressing EGFRvIII alone [13].