Both lung-resident cDC1s and cDC2s are able to elicit a strong Th2 response upon house dust mite (HDM) exposure [235–237], while CD103+ cDC1-deficient mice exhibit attenuated AHR and eosinophilia upon ovalbumin-induced asthma [238]. The gene discussed is ITGAE; the disease is Increased total eosinophil count.