Overall, although the TFIIIB subunits BRF216, 24, 25, 26, 28, 29, 30, 32, 34, 35 and BRF120, 21, 23, 24, 57 have been demonstrated to be deregulated in a variety of human cancers, the data presented in Figure 2 suggest that BDP1 is the only TFIIIB subunit specifically altered in serous ovarian cancer. Here, BDP1 is linked to cancer.