This activation of FAK in melanoma cells is driven in part by a “paradoxical” activation of melanoma‐associated fibroblasts and the induction of β1/FAK/SRC signaling (Hirata et al, 2015) but also after activation of GFRA2/GDNF expression and AKT activation (Marin‐Bejar et al, 2021). Here, PTK2 is linked to melanoma.