SOD1 and amyotrophic lateral sclerosis: First, Chiu et al. (2013) utilized flow cytometry and deep RNA sequencing to indicate that microglia isolated from the SOD1 (G93A) mutant mouse model of amyotrophic lateral sclerosis (ALS) differed from SOD1 (WT), LPS-induced microglia, and M1/M2 macrophages.