Specifically, Pin1 may be associated with excitatory glutamate receptors N-methyl-D-aspartic acid [(NMDA) receptors and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors] as well as inhibitory neurotransmitter receptors gamma-aminobutyric acid [(GABA) receptors and glycine receptors], which can effectively regulate the release of neurotransmitters and are significant in the progression of epilepsy. The gene discussed is PIN1; the disease is epilepsy.